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Open Source Pharmacology

·1144 words·6 mins
Demetrio Cantu-Alanis
Author
Demetrio Cantu-Alanis
No man stumbles upon the same river twice

For all of the troubleshooting, and optimization, and grocery shopping, and diet advice, and staving off hunger, and mouthfuls of honey… it could’ve all been averted had I just had someone tap me on the shoulder and say “Just take reta bro”.

Then instantly: more shredded, happier, hotter, not hungry, less addiction-forming. No need to maneuver my way around the peat-verse and fucking put together the most peatiest diet plan ever devised just to lose 5 pounds and eat more sugar.

No need to figure out the ideal grocery list. No need to calculate every single micronutrient that goes into my body.

“Just take reta bro”

That would literally save this country. So many people plagued by insecurity. So many people who have been overweight their whole lives. So many clients I’ve helped who’ve struggled with a lifetime of their bodies not cooperating with them. Hunger receptors frying them.

“Just take reta bro”

And it’s all fixed. No need to suffer. No imaginary badge for “having done it the right way”. No need to keep paying for an expensive personal trainer. No need to keep trying to be perfect to get a result other people seem to get effortlessly. You just get your result and move on with your life.

Many things are like this.

Modafinil for one, reta for another, testosterone, accutane, finasteride. Just one stop solutions that get you your result.

Modafinil = productivity. congrats you can finally work towards your goals at a meaningful capacity.

Testosterone = physique + motivation + aura, at the cost of your skin, water retention, and maybe your health if you’re not careful. I avoid it, if it didn’t age the shit out of you I’d probably be on it.

Accutane/Tretinoin = no more acne. simple as. Tretinoin has the added anti-aging benefit that Accutane doesn’t have. Your face is now frozen in time, not to age any longer. congrats.

Finasteride = congrats you have hair again. dutasteride if finasteride isn’t doing it for you. it comes with side effects though, be prepared to stave those off if you’re not on testosterone (there’s a reason why a lot of the people who preach finasteride are on TRT, they literally do not feel the negative side effects (which are definitely real) because they shut down their testosterone production and rely on exogenous hormones) that’s not to say that you need to be on trt to do finasteride, you can definitely do it with minimal side-effects natty, but it’s a lot easier if the entirety of your male hormones come to you via syringe rather than dealing with the complications in your own biology. No need to apply minoxidil to your scalp every night. No need to inject your scalp with bee venom or wash your hair with eggs and go on a Paul Saladino-esque health crusade where you eliminate every single micro-toxin and freak out at the thought of eating seed oils. Just take a pill, move on with your life, and your hair grows back.

Almost every major problem faced in the first-world today can be addressed in this manner by pharmacology.

Obese -> Reta -> No longer obese

Where this feels “wrong” is in the justified lack of trust in our medical industry. We know that big pharma doesn’t have our best interests in mind, or that they may prescribe us something we may not need or which may cause more side-effects which need to be treated with more of their drugs, ultimately resulting in more money in their pockets and less in yours.

(You could also feel like you are not worthy of your result which is a different issue entirely, you need to work on your self-image and subconscious but that is for a different time)

This is where the Modafinil vs Adderall distinction comes in.

Adderall is extremely addictive (it’s literally meth), works via a completely unsustainable mechanism which requires you to take more to feel the same high. IT GETS YOU HIGH. Comes with a host of side effects. This is the primary solution that big-pharma has for kids that have trouble sitting still in class. Lots of fucked up brains, fucked up lives, but hey fair play I’m sure it’s made them a buck by creating tons of dependent customers. (Sidenote about adderall: I’ve heard it can make you devoid of empathy and emotionless. I’ve read anecdotes of parents who’ve taken their kids off adderall because they started “behaving like businessmen”. Also had friends who seemed to lose all empathy once on it. Just a thought.)

Then you have something like modafinil, approved for narcolepsy, increasingly being used in place of adderall for ADHD patients though it’s still technically off-label use. Doesn’t flood your dopamine receptors, instead it just keeps the dopamine you naturally produce in the receptor for longer. Safe side-effect profile. Shown non-toxic and non-lethal even at completely ridiculous doses. Non-habit forming. Doesn’t get you high. You literally get all of the upside with the only downside being that you need to find a choline supplement to avoid getting a headache. That’s about as win-win as it gets.

And yet everybody knows about adderall, barely anybody knows about modafinil unless they’re in the chronically online peptides/nootropics/esoteric-health space.

BPC-157 is probably the best example of this. Here’s a drug that had made it all the way to phase 3 human trials, made it with a way better side-effect profile than many currently FDA approved compounds, but got pulled off the market due to the company manufacturing it being bought out by another company… then bought by another company… all of whom decided it would not be profitable to continue with the FDA approval process. And now if you take it to heal your gut lining, to heal an injury that’s plaguing you, or use it to make your joints more resilient if you’re in a joint-intensive sport like say BJJ, you’re “cheating”, you’re “literally injecting research chemicals”, “that doesn’t seem safe bro you sure about that BCP? You heard about it on the internet? I dunno bro”. Yes bro. It’s okay to take research chemicals. It’s okay to take your health into your own hands. No one else is going to do that for you.

This isn’t to say “the illuminati is poisoning you bro, big pharma wants your money bro”, yeah no shit. This is to say that there are legitimate solutions to your biological problems LIKE obesity, LIKE hair-loss, LIKE lack of focus/productivity, LIKE annoying injuries. Not all of them are perfect, finasteride is probably the best example of not being perfect, but the solutions are there and you can legitimately get a result that exceeds what big pharma markets whatever their newest drug to be, with a little bit of research, and a willingness to experiment.

Just do your research. Don’t fuck yourself up.

Best, Demetrio